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Everything may seem to go wrong for the villainous Dr. Horrible, but life's peachy for Neil Patrick Harris, the actor who plays the bumbling baddie in the eponymous Internet musical. He's moved on from life as Doogie Howser, M.D., and was recently nominated for an Emmy for his role in the sitcom How I Met Your Mother.

Brian de Palma is one of cinema's most hypnotic stylists, a virtuoso who can expand your perception of space, time and motion onscreen. So when he throws away his jazzy technique and goes for rough-hewn and immediate — as in Redacted — it's a major statement.

Matthew Diffee contributes regularly to the cartoonists' bible, The New Yorker. But that magazine gets more than 500 submissions a week — and publishes only 20 cartoons in each issue. Diffee's new book, featuring his work and that of other New Yorker regulars, is The Rejection Collection, Vol. 2: The Cream of the Crap.

Filmmaker Brian De Palma has been making movies and stirring controversy for more than 40 years. His films include Scarface and Casualties of War; his new Redacted retells a true story about a rape and murder committed in Iraq by U.S. soldiers.

NPR's Don Gonyea plays the puzzle with puzzlemaster Will Shortz and listener Cat Dickey of New Orleans.

Falguni Adams plays the puzzle with puzzlemaster Will Shortz and NPR's Ayesha Rascoe.

The modern Bible is the product of translations and interpretations that span centuries. But a true understanding of its meaning should take into account its origins in Jewish culture, according to biblical scholar Marc Zvi Brettler, author of How to Read the Bible.

Mark Englehart plays the puzzle with puzzlemaster Will Shortz and NPR's Ayesha Rascoe.

Journalist Karl Fleming's new book is Son of the Rough South: An Uncivil Memoir. As a civil rights reporter for Newsweek in the 1960s, he wrote about major events such as the Birmingham church bombing, the assassination of Martin Luther King, Jr., and the murders of three civil rights workers in Philadelphia, Miss. While at the 1966 riots in the Watts section of Los Angeles, Fleming was severely beaten.

Fear and paranoia often take hold when a disease threatens to become an epidemic. Dr. Marc K. Siegel is the author of the new book Bird Flu: Everything You Need to Know About the Next Pandemic.